abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to novel 3-phenyl-3-methoxypyrrolidine derivatives of formula , to any of its enantiomers or any mixture of its enatiomers, or its N-oxides, or its deuterated analogues, or its pharmaceutically acceptable salts, where R 1 stands for F, Cl; R 2 stands for F, Cl; R 3 stands for H, CH 3 or CH 2 CH 3 ; on condition that the said compound does not represent 3-(2,4-difluorophenyl)-3-methoxypyrrolidine and 3-(3,5-difluorophenyl)-3-methoxypyrrolidine. n EFFECT: compounds are useful for a modulation of extracellular levels of dopamine and norepinephrine catecholamines in areas of the mammalian brain cortex, which makes it possible to use them for treatment of the nervous system disorders. n 11 cl, 1 tbl, 51 ex |