| abstract |
FIELD: medicine. n SUBSTANCE: claimed invention relates to immunology and biotechnology. Claimed are: a pharmaceutical composition and a method, based on an introduction to a patient of a therapeutically efficient amount of an antibody against CD200, which contains G2/G4 constant region, for treatment of the patient with malignant neoplasm, containing CD200 positive malignant cells. The said antibody against CD200 inhibits interaction between CD200 and CD200R. n EFFECT: application of the invention ensures better inhibition of the tumour growth with reduced effector function in comparison with application of the antibody, containing G1constant region, which can be applied in medicine. n 24 cl, 29 dwg, 6 ex |