| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to derivatives of nucleosides, based on them compositions and methods of treating liver disorders, mediated by Flaviviridae infection, including hepatitis C. The said derivatives of nucleosides include , where R 1 represents hydroxyl, amino or benzylamino; and R 2 represents hydrogen, , , or , and when R 1 represents hydroxyl, R 2 is different from hydrogen, and, , when R 1 represents benzylamino, R 2 is different from . n EFFECT: novel effective antiviral compounds are claimed. n 43 cl, 64 tbl, 18 ex, 6 dwg |