http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2519103-C2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93d78287128f7fd3c684a99246243020
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22
filingDate 2012-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ce923ccd24443f43df8e9b33e4f8a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4305d975b2ddec82de14c8586a1c581
publicationDate 2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2519103-C2
titleOfInvention Bioresorbable hydrogel polymer composition with biologically active substances (versions)
abstract FIELD: medicine. n SUBSTANCE: invention refers to medicine. What is described is a bioresorbable hydrogel polymer composition for cardiovascular surgery in the form of a film prepared by a reaction of natural polymers, biologically active substances, a solvent and a softening agent wherein the polymers are presented by cross-linked bioresorbable polymers - gelatin, chitosan or a mixture of chitosan and gelatin, chitosan and polyhydroxybutyrate; the biologically active substance or mixtures thereof are presented by the antioxidant L-carnosine, the anticoagulant heparin, the antiaggregant dipyridamole, acetylsalicylic acid, the non-steroid anti-inflammatory preparation acetylsalicylic acid, the antimicrobial preparations - ciprofloxacin, metronidazole; mechanical strength of the film is not less than 1.2 MPa, the relative elongation is no more than 160%, and the elasticity modulus is 0.4-5 MPa. n EFFECT: there are used hydrogel polymer compositions with the control bioresorption period, prolonged length of biologically active substance release, having biocompatible and thrombus-resistant properties and improved mechanical characteristics - higher softness and elasticity. n 7 cl, 12 dwg, 2 tbl, 4 ex
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2796007-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2624280-C1
priorityDate 2012-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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