abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to compound of formula , where Z stands for phenyl, substituted with 1-5 halogen atoms, selected from fluorine and chlorine; R 4 stands for C 1 -C 4 -alkyl with linear chain or C 3 -C 4 -alkyl with branched chain; or to its pharmaceutically acceptable salt. Invention also relates to pharmaceutical composition, inhibiting prolyl hydroxylase activity, based on said compounds. n EFFECT: obtained are novel compounds and based on them pharmaceutical composition, which can be applied in medicine for treatment of diseases, associated with immune response of organism. n 18 cl, 20 dwg, 8 tbl, 13 ex |