| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to compounds of formula (I), in which a represents 0, 1 or 2; each R 1 independently represents halogen or trifluoromethyl; R 3 represents hydrogen, halogen or -C 1-6 alkyl; R 4 , R 5 and R 6 independently represent hydrogen or halogen; or to their pharmaceutically acceptable salt. Invention also relates to methods of obtaining said compounds and pharmaceutical composition, possessing activity as serotonin (5-HT) and norepinephrin (NE) reuptake inhibitors, on their basis, and to intermediate substances for obtaining similar compounds. n EFFECT: obtained are novel compounds and based on them pharmaceutical composition, which can be applied in medicine for treatment of disorders accompanied by pain. n 31 cl, 6 ex |