| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to compound of formula (II), where Q represents S, dashed line represents double bond; R 1 represents phenyl, pyrimidinyl, thienyl, indolyl; R 2 represents phenyl; and each R 3 , R 4 and R 5 independently represent hydrogen, methyl, ethyl, nitro, cyano, F, Br, CF 3 , amino, OCH 3 ; or to its pharmaceutically acceptable salt. Invention also relates to pharmaceutical compositions, possessing anti-cancer activity, which contain claimed compounds. n EFFECT: obtained are novel compounds, which can be applied in medicine for treating cancer, where cancer is selected from group, consisting of prostate cancer, breast cancer, ovary cancer, skin cancer, lung cancer, large intestine cancer, leukemia, kidney cancer, CNS cancer, and their combinations. n 18 cl, 5 dwg, 5 tbl, 9 ex |