| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to novel intermediate compounds of structural formulas 2, 4, 5, 6, 7, 9, 10, 11, 12, 16, given in the invention formula. Said compounds are used for obtaining NEP-inhibitor, which represents N-(3-carboxy-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methylbutanic acid or its pharmaceutically acceptable salt, or its pro-drug, representing ethyl ether of N-(3-carboxy-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methylbutanic acid or its salt. n EFFECT: obtaining novel compounds. n 12 cl, 6 dwg, 77 ex, 4 tbl |