abstract |
FIELD: chemistry. n SUBSTANCE: disclosed are compositions having sodium-dependent glucose cotransporter n n n n n (SGLT) inhibiting effect, having a structure given below, where values of radicals are given in the claim. Also disclosed is a method of treating or preventing a disease influenced by SGLT inhibition, where said disease is: type 1 sugar diabetes, type 2 sugar diabetes, hyperglycemia, diabetic complications, insulin resistance, metabolic syndrome (Syndrome X), hyperinsulinemia, hypertension, hyperuricemia, obesity, oedema, dyslipidemia, chronic heart failure or atherosclerosis. n EFFECT: invention also provides pharmaceutical compositions and methods for deuterium-enrichment of a diaryl methyl compound, having a structure given below, where values of radicals are given in the claim. n 37 cl, 7 dwg, 6 tbl, 64 ex |