http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2507269-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_897ff9390f06b5b6e84a99034a822e7d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_871b79c82aeb7027ab2ef51a9d12dd50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8452aefb51b44e631fe15a3a3f064ded http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1316dbe52efe40b0c69edbc10420603d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e12df703fb380e0e91d50555105905ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bac668b5eaa9cfb8d3751251298f271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eda81a29a7a0d052733f168c41637810 |
| publicationDate | 2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2507269-C2 |
| titleOfInvention | Edwards syndrome determination technology by sequenation method |
| abstract | FIELD: biotechnologies. n SUBSTANCE: method for determination of foetus Edwards syndrome, where from pregnant women plasma extracted is extracellular DNA, it is subjected to disulfide conversion succeeded by polymerase chain reaction and further mass parallel sequenation of differential methylated sites; as control of differential methylated sites used are sites with various levels of methylation of a mother and a foetus, data are analysed by determination of relation of reading quantities obtained by sequenation of differential methylated sites of DNA on purpose and control chromosomes, where in case of trisomyunder constant quantity of foetus DNA readings, charted on differential methylated sites of chromosomes there will be observed quantity of readings charted on purpose chromosome to quantity of readings on control chromosomes equal to 3/2, while as a norm this relation will be constant equal to 1. n EFFECT: method may be used in medicine for prenatal diagnostics of foetus transmittable diseases. n 3 cl, 1 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2712175-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2642622-C2 |
| priorityDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.