| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to novel compounds derived from taurine having formula , wherein R is selected from 2-(6-methoxy-2-naphthyl)propionic acid, [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid and salts thereof. The invention also relates to a method of producing compounds of formula (I) by reacting taurine with a compound belonging to a group of non-steroid anti-inflammatory preparations comprising 2-(6-methoxy-2-naphthyl)propionic acid, [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, in the presence of a catalyst in a corresponding organic medium, and anti-inflammatory pharmaceutical compositions containing at least one compound of formula I, having non-steroid anti-inflammatory activity. n EFFECT: improved characteristics of compounds. n 8 cl, 4 tbl, 10 dwg, 6 ex |