http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2493257-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b9abcb38fd002b91c7218745fd1d366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_493180c321dbd20ba1f82fbdf61fa248 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01086eb4b08f4f467cfe91b24b8bd3e8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-06 |
| filingDate | 2012-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be4290d0161054ff01e3e4e932293fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07d260546a9949b8e1eca13aa51fe286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b57ea691999ee10ecfee09a158d1f914 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e92578cf6e7e893653face52e25eee98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_676572fc7278fb39115bf98fcfed85b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360943385568d768a11f916631349526 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51c58c3152f9a38caa4936f279ff087c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97bd54e177eddea72d1d5bf5cb0cfcb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8141995f9b8169da5eecd09fe5ee30c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84a675c1f21428ab5b55e61467f3cabd |
| publicationDate | 2013-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2493257-C1 |
| titleOfInvention | Method to produce adjuvant |
| abstract | FIELD: biotechnologies. n SUBSTANCE: method includes cultivation of a fungus of Fusarium sambucinum type on nutrient medium containing a source of carbon 3-4%, nitrogen 0.2-0.3%, phosphorus 0.2-0.3% and microelements 0.07-0.08%, under sterile conditions at temperature of 26-30°C with mixing and aeration within 36-72 hours with subsequent separation of the cultural liquid from fungus biomass. Besides, the cultural fluid is centrifuged at room temperature for 15-20 min. at 800-1500 rpm, and the target product is made from supernatant by separation of peptides with molecular mass from 3,000-60,000 D. Also before centrifugation the cultural fluid is heated up to 110-115°C and pressure of 1.3-1.5 atm. with rate of 1.5-2 degrees/min. with the following exposure for 1.5-2.5 hours. n EFFECT: adjuvant prepared in accordance with the invention has higher potency that stimulates immunity, is harmless within vaccines and other products of immunological purpose, areactogenic, may be applied both independently and in combination with oil adjuvants or adjuvants-sorbents on the basis of aluminium hydroxide gel and other substances. n 2 cl, 3 tbl, 9 ex |
| priorityDate | 2012-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.