| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to antibacterial compounds of formula (I) , where one or two of U, V, W and X represent N, the remaining ones represent CH or, in case X, can also represent CR a , where R a represents fluorine; R 1 represents alcoxygroup, halogen or cyanogroup; R 2 represents H, CH 2 OH, CH 2 N 3 , CH 2 NH 2 , alkylcarbonylaminomethyl or triazol-1-ylmethyl; R 3 represents H or, when n=1, R 3 can also represent OH, NH 2 , NHCOR 6 or triazol-1-yl; A represents CR 4 ; K represents O, NH, OCH 2 , NHCO, NHCH 2; CH 2 NH 5 CH 2 CH 2 , CH=CH, CHOHCHOH or CHR 5 ; R 3 represents H or together with R 5 forms bond, or R 4 can also represent OH, when K is not O, NH, OCH 2 or NHCO; R 5 represents OH or together with R 4 forms bond; R 6 represents alkyl; m=0 or 1 and n=0 or 1; and G is specified in i.1 of the formula; and to salt of such compound. n EFFECT: obtaining antibacterial compounds. n 19 cl, 1 tbl, 44 ex |