http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2491282-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dc6e1791435cbb6c414efa7ceb09aa0 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
filingDate | 2008-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28dbb4fd8fc0e4ebae6695577a6b36dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c8d88661eba4cd4aae408f0db440c8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bac9de77ab8437c18a42fb795358ab8e |
publicationDate | 2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2491282-C2 |
titleOfInvention | Compounds for treating cancer |
abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to a method of treating cancer in a patient, wherein the method involves administering a cancer-inhibiting amount of a compound of formula I into a patient's body. The method of treating cancer in the patient, including a human, wherein the method involves administering the cancer-inhibiting amount of a first compound of formula I or a physiologically acceptable salt thereof into the patient's body, wherein X represents CH or N, each R 1 independently represents hydrogen or -CH 2 COR 5 ; R 5 represents hydroxy, optionally hydroxylated alkoxy, amino or alkylamino; each R 2 independently represents the group ZYR 6 ; Z represents a bond or the C 1-3 alkylene or oxoalkylene group optionally substituted by the group R 7 ; Y represents a bond, an oxygen atom or the group NR 6 ; R 6 is a hydrogen atom, the group COOR 8 , the alkyl, alkenyl, cycloalkyl, aryl or aralalkyl group optionally substituted by one or more groups COOR 8 , CONR 8 2 , NR 8 2 , OR 8 , =NR 8 , =O, OP(O)(OR 8 )R 7 and OSO 3 M; R 7 is hydroxy, the optionally alkoxylated or aminoalkyl group; R 8 is a hydrogen atom or the optionally hydroxylated, optionally alkoxylated alkyl group; M is a hydrogen atom or one equivalent of a physiologically acceptable cation; R 3 represents the C 1-8 alkylene group, 1,2-cycloalkylene group or 1,2-arylene group, optionally substituted by R 7 ; and each R 4 independently represents hydrogen or C 1-3 alkyl. n EFFECT: invention refers to a pharmaceutical composition for treating cancer in the patient, containing the compound of formula I, as well as to a kit for treating cancer. n 23 cl, 3 ex, 7 dwg |
priorityDate | 2007-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.