http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2490024-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdea8d588e41d2594bbda4bb4c9e6703 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-29 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04 |
| filingDate | 2007-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2383e6921b1890019e9cce82a464fa6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a9221f148147ffb6d2fba874cbf62e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d2b4579d257b67a0e555eebd62fcc82 |
| publicationDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2490024-C2 |
| titleOfInvention | T cell spectrum broadening for sub-dominant epitope inclusion by vaccination with antigens delivered as protein fragments or peptide cocktails |
| abstract | FIELD: medicine. n SUBSTANCE: group of inventions is based on the induction of recognising dominant and sub-dominant responses to epitopes of any antigen important for preventing or treating a chronic diseases by immunisation with pools of overlapping fragments of a desired antigen. A T cell spectrum is primed to be included both for a principal epitope recognised when using an intact molecule for immunisation and induced by a chronic infection, and for inducing a much wider and more balanced response to the number of the sub-dominant epitopes. An elicited T cell response to the sub-dominant epitopes is important to protect against the chronic disease which itself induces the response focused on the principal epitopes only. n EFFECT: group of inventions requires no advance information on the exact localisation and identity of the sub-dominant epitopes, as well as recognition thereof in the human population, and extends the range of T-cells and thereby total number of epitopes recognised by the specific T cells primed by vaccination against several principal epitopes to the variety of the epitopes of the vaccine importance. n 12 cl, 13 dwg, 5 ex |
| priorityDate | 2006-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.