http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2489429-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b4a41ab34ae17693c1e5d5d97880fa9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-51 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aaa6d7b4122b17612df614c315c80d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_880fe38a56ea8e347f14ba021984ab6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701c5f51e00813c9447b0d7fee7702fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f0a06c6925d087dcb6b5b1235decf74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_393edebbb2981da73045736cb6c29b74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce21ead00a814a9293b2ff0d356ad8a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a53dbc8b1705395157dd4cc8cb1bb63 |
| publicationDate | 2013-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2489429-C2 |
| titleOfInvention | Antitumoral compounds |
| abstract | FIELD: biotechnologies. n SUBSTANCE: invention relates to compounds of general formula I, having cytostatic or cytotoxic activity, its pharmaceutically acceptable salts, tautomers or stereoisomers, a pharmaceutical composition on their basis. Compounds may be used for treatment of cancerous diseases. In the general formula I n n n n Y is selected from the group comprising -CHR ay - and -CHR ay -CR by -CR cy -; each R ay , R by and R cy are independently selected from hydrogen and non-substitute C 1 -C 12 -alkyl; each R 1 , R 2 , R 3 , R 4 and R 5 are independently selected from hydrogen and non-substitute C 1 -C 12 -alkyl; R 6 is selected from NR 8 R 9 and OR 10 ; A means , W means NR 7 ; R 7 means hydrogen; R 8 means hydrogen; R 10 means non-substitute C 2 -C 12 -alkenyl; each dotted line means unnecessary additional link, but when there is a triple link between atoms of carbon, to which R 1 and R 2 are attached, then R 1 and R 2 are absent, and when there is a triple link between carbon atoms, to which R 3 and R 4 are attached, then R 3 and R 4 are absent; R 9 is selected from substitute C 2 -C 12 -alkenyl and substitute C 4 -C |2 -alkenylyl, where substitutes are selected from the group, consisting of: halogen, OR', OCONHR' and OH, protected with a simple silyl ether; where R' means hydrogen; provided that whenever Y means -CHR ay -CR by =CR cy - and there is a single or double link between atoms of carbon, to which R 3 and R 4 are attached, then R 9 means substitute C 4 -C 12 -alkenylyl; and each R 16 , R 17 and R 18 are independently selected from hydrogen and OR a ; each R a is selected from hydrogen or non-substitute C 1 -C 12 -alkyl. n EFFECT: higher efficiency of compound application. |
| priorityDate | 2007-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 351.