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filingDate 2012-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d32c28ca3e46c5f2c4e9f9668d6b4c1
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publicationDate 2013-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2487930-C1
titleOfInvention PREPARATION WITH POLYFUNCTIONAL MEDICAL-BIOLOGICAL ACTIVITY THAT INFLUENCES TISSUE EXCHANGE BASED ON FUNGUS STRAIN Pleurotus ostreatus VKPM F-819
abstract FIELD: biotechnologies. n SUBSTANCE: preparation with polyfunctional medical-biological activity that influences tissue exchange is produced as a result of liquid-phase depth cultivation of fungus Pleurotus ostreatus All-Russian collection of industrial microorganisms F-819 with further separation of mycelium and cultural liquid and extraction of biologically active substances in the form of a condensed extract from the mycelium. The produced extract, which represents a pharmacological substance of a preparation, is enriched with the agent of the derivative of sterol 4-hydroxy-17P-methylinecisterol with molecular weight of 332.2452 Dalton, polysaccharide β 1-3 glucan and dihydroquercetine with molecular weight of 304.26 Dalton. At the same time the specified components are taken at the following weight ratio: (1):(2):(3):(4) as (79.0-158.0):(1.0-2.0):(10.0-20.0):(10.0-20.0). n EFFECT: invention makes it possible to increase quality of a preparation as a result of increasing its antitumoral activity and reduced toxicity of preparations of antitumoral chemotherapy with simultaneous application with the suggested preparation. n 2 cl, 21 dwg, 11 tbl, 2 ex
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