http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2485517-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54ac25d0c50f692f2ccee2f291b474d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cc8d7d5b1e9647ea47da6fe6c6945c6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2011-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9624ef753076685b1c558b5b6b08a2b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38d9d38e24abd5a05be58e5ba6ffada1 |
| publicationDate | 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2485517-C2 |
| titleOfInvention | Diagnostic technique for degree of thyroid carcinoma |
| abstract | FIELD: medicine. n SUBSTANCE: what is used is a fine-needle puncture aspirate biopsy of thyroid nodules. The prepared punctates are used to prepare smears, and light-microscopic immunocytochemistry is conducted, thyroglobulin expression is determined. Thereafter, atomic force microscopy is applied to determine a height of cell cytoplasm and a height of the immune complexes formed using thyroglobulin as a marker. Then, the derived data are assessed, and adequate points are assigned thereto. Manifested thyroglobulin expression is 6 points, medium expression is 4 points, weak expression is 2 points, no expression is 0 points. The height of cell cytoplasm less than 100 nm stands for 0 points, 100-200 nm - for 2 points, 200-260 nm - for 4 points, more than 260 nm - for 6 points. The height of immune complexes of 800-950 nm means 6 points, of 400-460 nm - 4 points, of 100 nm and lower - 2 points, if the height of immune complexes is zero, 0 points are assigned. Then, the points are summed, and a degree of malignancy of thyroid carcinoma is determined: 18 points means high-differentiation carcinoma, 12 points - medium-differentiation carcinoma, 6 points - low-differentiation carcinoma, 0 points - undifferentiated carcinoma. n EFFECT: method enables improving the diagnostic accuracy of thyroid carcinoma and a degree of malignancy. n 1 tbl, 1 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2553378-C1 |
| priorityDate | 2011-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.