http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2484812-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0386387c72578255f11416b50e644519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-26 |
| filingDate | 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b96e1576ff14a678b0bde59a835c64a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61314f4fb9d32700878d9d2659d95e0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3c67b7c7f6fe4865dbdc48830372cad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cea1b2e2eabffc3e9a06115e2b0cff2 |
| publicationDate | 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2484812-C1 |
| titleOfInvention | Method of obtaining sorbent based on inorganic porous granules and polyhydroxyfullerene for removing atherogenic lipoprotein from blood plasma |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: group of inventions relates to methods of obtaining sorbent for separation of atherogenic low density lipoproteins (LPLD) from blood plasma. One of methods includes preliminary heating of inorganic porous granules of silica gel to 120-150°C, hard phase reaction of preliminarily heated silica gel with polyhydroxyfullerene C 60 (OH) 12-24 at pressure 10 -5 mm Hg and temperature 120°C and following mixing for 50-60 h. Also claimed is method for removing LPLD, which includes preliminary heating of inorganic porous granules of silica gel to 120-150°C, addition of dimethyldichlorosilane at 120°C and 10 -5 mm Hg, with reaction ~Si-OH+Cl 2 SiMe 2 →~Si-O-Si(Me 2 )Cl taking place. After that, dimethyldichlorosilane that did not react, is removed, solution of polyhydroxyfullerene C 60 (OH) x , where x= 12-24 in dry tetrahydrofuran is added to chlorinated silica gel and reaction -(Me 2 )Si-Cl+C 60 (OH) 12-24 →~Si-O-(Me 2 )-Si-O-C 60 (OH) x-1 is carried out for a day. Then excess of reagent is removed and obtained sorbent is washed. n EFFECT: invention insures obtaining sorbents with high selectively adsorptive capacity with respect to LPLD. n 2 cl, 4 tbl, 2 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2545693-C1 |
| priorityDate | 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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