http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2482487-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_284b7eb0166753baf1dc7da0aee426bd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49 |
| filingDate | 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e2e974b49b98f667dc44488ee561c0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cf3d66ce47adcca553f21c0039c2da0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c2e2c4a4130f32b99311e0d3528c5d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a5f181f9bd9df4247b02c502fc17ca1 |
| publicationDate | 2013-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2482487-C2 |
| titleOfInvention | Method for evaluating lymphocyte effect on developing endothelial dysfunction |
| abstract | FIELD: medicine. n SUBSTANCE: patient's peripheral venous blood 5 ml is taken; blood 2 ml is centrifuged in ficoll-verografin density gradient ρ=1077. Phase-contrast microscopy is used to count lymphocytes in 10 visual fields per 4 cm 2 to determine cytoplasm membrane vesiculation. The lymphocyte and microparticle coefficients are calculated providing the following criteria: lymphocyte count up to 100 cells in 10 visual fields corresponds to coefficient 1, more than 100 cells - to coefficient 2, endothelial microparticle count in 10 visual fields up to 50 pieces corresponds to coefficient 1, more than 50 pieces - to coefficient 2. Further, these coefficients are related: if the vesiculation lymphocyte and endothelial microparticle coefficients are related as 1:1, then the involvement of lymphocytes in developing endothelial dysfunction is stated, and the vesiculation and microparticles related as 2:1 show the low involvement of the lymphocytes in developing dysfunction endothelium, while the vesiculation and microparticle coefficients related as 1:2 or 2:2 enable stating the severe endothelial dysfunction. n EFFECT: invention ensures evaluating the severity of the endothelial dysfunction that provides a basis to predict the risk of developing vascular complications and optimising the treatment of cardio-cerebrovascular diseases. n 4 dwg, 4 tbl, 5 ex |
| priorityDate | 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.