| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: group of inventions relates to medicine and deals with application of composition, which includes rotigotine in concentration, sufficient for providing flow of rotigotine, necessary for obtaining therapeutic effect, and, at least one chloride salt in concentration from 1 to 140 mmol/l, where said composition has pH from 4 to 6.5, for charging device for ionophoresis for treatment of Parkinson disease. n EFFECT: group of inventions provides flow of rotigotine through stratum comeum of humans, which is higher than flow, earlier obtained with application of conventional systems of passive diffusion. n 9 cl, 3 ex |