http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2477267-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_253de143b03bc8ee2bf61b3c64e32c35 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-194 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-40 |
filingDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc317ccfb3301b44c620993bdaab8277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dfc3961507bef46256767bec2216c53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c977bfef4b2f3d6e33dbbab85d1142 |
publicationDate | 2013-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2477267-C2 |
titleOfInvention | Water-soluble arylated c70 fullerene derivatives and method for production thereof |
abstract | FIELD: chemistry. n SUBSTANCE: invention relates to chemical industry and chemical functionalisation of fullerene C 70 , particularly a method for synthesis of organic derivatives of [70] fullerene, including those soluble in water and physiological media. More specifically, the invention relates to novel water-soluble derivatives of fullerene C 70 of general formula , where in general formula 1, X denotes a methylene group (CH 2 ), oxygen (O), sulphur (S), nitrogen (NH or NR, where R is an aliphatic acid residue -(CH 2 ) m COOH, where m ranges from 1 to 99); the number of methylene links n in the chain which binds the solubilising COOH group and a C 6 H 4 X fragment ranges from 0 to 99; as well as to a method of producing water-soluble arylated C 70 fullerene derivatives of general formula 1 upon reaction of chlorofullerenes with aromatic acid esters followed by hydrolysis, where the chlorofullerenes used are C 70 C 18 and/or C 70 Cl 10 chlorofullerenes. n EFFECT: invention can be used in biomedical research and in production of novel medical drugs for therapy in human and animal diseases. n 2 cl, 3 ex, 5 dwg |
priorityDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.