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publicationDate 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2476210-C1
titleOfInvention METHOD FOR ENHANCEMENT OF EFFICACY OF E.coli RESISTANT ANTIBIOTICS
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: method under the invention involves detoxification and polymerisation of the tested antibiotics 150-200 mg/ml at first in 0.15±0.05% glutaric aldehyde at 38-40°C for 2-3 days, then in 0.1% aethonium or 0.1% alkyl dimethyl benzyl ammonium or 0.1% Biopague D at 38-40°C for 2-3 days. n EFFECT: use of the method provides 1,5-2,0 times higher activity of the antibiotic as compared to commercial preparations and ensures the bactericidal efficacy to antibiotic-resistant Ecoli. n 2 ex
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