http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2475252-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63e6bc411b68c7b8b95beda1c8968aba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1f5dc9836cda6a8a32a5a404228079c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-805 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-18 |
| filingDate | 2011-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16cbf4613945ef7ce148d8105102d5f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b5dacafd907d66e105b0845ec34b96d |
| publicationDate | 2013-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2475252-C1 |
| titleOfInvention | Method for preparing high-temperature stable pharmaceutical composition containing oxygen carrier and using it |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: group of inventions refers to medicine, particularly a method for preparing a therapeutic preparation containing high-purity and stable hemoglobin as an oxygen carrier, a preparation and a method for tissue oxygenation. A method involves destruction of washed red blood cells with the use of hypotonic lysis, filtration, extraction, ultrafiltration, column chromatography, re-ultrafiltration to produce a concentrated hemoglobin solution containing no phospholipids and dimers, blocking of sulphhydryl groups, formation of a cross link by means of bis-3,5-dibromsalicylfumarate, addition of N-acetylcysteine, addition to a pharmaceutically acceptable carrier for producing a drug preparation. The method for tissue oxygenation involves using the produced preparation and is applicable in treating cancer. n EFFECT: group of inventions enables producing high-purity cross-linked tetramer haemoglobin (optionally containing ≥70% of β-β cross-links) with high effectiveness of oxygen transfer, stable at high temperatures and applicable for mammals with no risk of renal damage and vessel constriction. n 13 cl, 13 ex, 9 tbl, 17 dwg |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020080978-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2731450-C2 |
| priorityDate | 2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 284.