patent/RU-2473565-C2

http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2473565-C2

Outgoing Links

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assignee	http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae2273ce6db53472e50cff093f3b18
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classificationIPCInventive	http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
filingDate	2007-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate	2013-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor	http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70344a0f00c27087ee43bd6040a01d01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcf91855b0afa927b7e6a2fee879f483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13c0ad64c487aa3a9e9bd66a707d8ce3
publicationDate	2013-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber	RU-2473565-C2
titleOfInvention	HUMAN PROTEIN TYROSINE PHOSPHATASE BETA BINDING ANTIBODIES (HPTPβ), AND USE THEREOF
abstract	FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to medicine. What is presented is an antibody produced of hybridoma ATCC No. PTA-7580 specific to human protein tyrosine phosphatase beta (HPTPβ). What is described is a Fab version of said antibody, as well as versions of method of treating and pharmaceutical compositions based on the use of the antibodies. Binding the antibody and HPTPβ intensifies Tie-2 signal transmission, and thereby increases angiogenesis, whereas binding the Fab antigen-binding antibody fragment and HPTPβ inhibits Tie-2 signal transmission, and thereby reduces angiogenesis. n EFFECT: use of the invention can find application in medicine for treating the diseases related to disturbed angiogenesis. n 21 cl, 12 dwg, 1 tbl, 5 ex
priorityDate	2006-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type	http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate	Subject
isCitedBy	http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005260132-A1
isDiscussedBy	http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID505696 http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID19263 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419484026 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6057 http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5787 http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID314843

Total number of triples: 63.