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filingDate 2011-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2473367-C1
titleOfInvention Method for making stent for radiation therapy of bile duct malignancies
abstract FIELD: medicine. n SUBSTANCE: invention refers to nuclear medical equipment and relates to the development of a method for making polyethylene and Teflon biliary stents provided with a radionuclide-containing segment and applicable for endoscopic implantation into a bile duct for the purpose of radiation therapy of the malignancies. Making said stents involves the following stages: 1) preparing a three-layer membrane consisting of polyethylene or Teflon outer layer and an inner layer made of a composite sorbent of polyethylene or Teflon as a matrix, and ionite as an excipient, 2) fixation of a radionuclide in the inner layer of the membrane by filtration of an aqueous-alcohol radionuclide-containing solution, 3) washing of the membrane in the aqueous-alcohol solution, 4) drying of the membrane, 5) extrusion of the three-layer membrane. n EFFECT: method provides the reliable fixation of the radionuclide in the matrix of the polymer stent without disturbing a thickness homogeneity of the stent and eliminates an ability of radioactive segment destruction in the radiotherapy. n 5 cl, 4 ex
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