| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: what is presented is the use of a beta blocker for preparing a drug for treating hemangiomas, e.g. hemangiomas in infants. The beta blocker may represent alprenolol, bucindolol, carteolol, carvedilol, labetalol, levobunolol, medroxalol, mepindolol, metipranolol, nadolol, oxprenolol, penbutolol, pindolol, propafenone, propranolol, sotalol, timolol, their pharmaceutically accepted salts and mixtures. n EFFECT: what is shown is decreased proliferative activity of hemangiomas in infants under the effect of the non-selective beta-blocker propranolol, downsizing, flattening and discolouration of hemangiomas; treatment failures according to the declared invention are not found; in contrast to the use of an alternative - common corticosteroids, interferon or vincristine, usually used to treating hemangiomas; antiangiogenic action of the beta blocker in hemangiomas is shown, and the beta-2 adrenoceptor are expressed on hemangioma endotheliocytes. n 19 cl, 6 dwg, 3 ex |