http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2470072-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0be9aa10b321831ecc0eb6866bf3b8a5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-23 |
filingDate | 2011-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7a2c239dbf7ad9b1620156339cbf3a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_568b9eedab3cfcb6204dcbecf6142f60 |
publicationDate | 2012-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2470072-C1 |
titleOfInvention | RECOMBINANT PLASMID DNA pGD-14 CONTAINING HYBRID GENE, INCLUDING NUCLEOTIDE SEQUENCE OF DEXTRAN-BINDING DOMAIN OF BETACOCCI, JOINED WITH HUMAN INTERFERON-GAMMA GENE THROUGH ACID-LABILE SPACER, DETERMINING BIOSYNTHESIS OF CHIMERIC PROTEIN STRUCTURE |
abstract | FIELD: chemistry. n SUBSTANCE: invention relates to biotechnology and can be used to obtain recombinant human interferon-gamma gene. Plasmid DNA pGD-14 is constructed, which determines expression in Escherichia coli bacteria cells of a genetically engineered structure consisting of an N-terminal sequence of a dextran-binding domain of betaccoci and the human interferon-gamma gene, which are joined in a single reading frame through an aspartate-proline acid-labile spacer. n EFFECT: invention provides stable expression of the dextran-binding domain of betacocci and human interferon-gamma gene at 20% of the total protein of the transformed Escherichia coli cell. n 3 dwg, 3 ex |
priorityDate | 2011-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 176.