http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2469093-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88fd16d00be754ab038b306f43995699 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea3a6dffaf4320cf4a48896e10cef6bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbc689cf97191a8958640e0cc1143e5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e581680152dad5947b9b0a0974a59540 |
publicationDate | 2012-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2469093-C2 |
titleOfInvention | EXPRESSION PLASMID DNA pCID-PROC CODING HUMAN PROTEIN C AND CELL LINE DG-CID-PROC-1 PRODUCING RECOMBINANT HUMAN PROTEIN C |
abstract | FIELD: medicine. n SUBSTANCE: invention refers to biotechnology, namely plasmid DNA pCID-PROC for expression of recombinant human protein C, cell lines of Chinese hamster ovary DG-CID-PROC-1 and a method for producing recombinant human protein C. The presented invention may be used for producing recombinant human protein C. Plasmid DNA pCID-PROC for expression of recombinant human protein C contains a sequence of full-length complementary DNA of a human protein C gene presented in List of Sequences as the sequence SEQ ID NO: 1. Plasmid DNA pCID-PROC is characterised by a physical map presented on dwg. 1. A cell line of Chinese hamster ovary DG-CID-PROC-1 is produced by transformation of the cell line of Chinese hamster ovary DG-44 by said expression plasmid DNA pCID-PROC. The method for producing recombinant human protein C involves culture of said cell line DG-CID-PROC-1 in a nutrient medium and recovery of produced target protein from a culture fluid. n EFFECT: invention provides higher production performance of the protein C expression system and simplified recovery, activation and purification of recombinant activated human protein C. n 3 cl, 3 dwg, 2 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2552170-C2 |
priorityDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 174.