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filingDate 2007-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff00a4401e5e28bd4d69c4bfe357c995
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4116bb914be9be719ba4194380df79da
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publicationDate 2012-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2467750-C2
titleOfInvention Niacin-containing pharmaceutical composition (versions) and tablet preparation, method for reducing hyperemia and method for preparing niacin-containing tablet
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to a pharmaceutical composition containing niacin 1000 mg. The composition contains 78 to 82 wt % of granulated niacin, with 85 wt % of granulated niacin having a particle size within the range of 100 to 425 mcm and no more than 10 wt % of granulated niacin having a particle size less than 100 mcm. Also, the composition contains 14 to 18 wt % of hydroxypropyl methyl cellulose of a methoxy substitution degree within the range of 1.39 to 1.41 and hydroxyl propoxyl molar substitution within the range of 0.20 to 0.22, 2.5 to 3.0 wt % of polyvinylpyrrolidone and 0.5 to 1.5 wt % of stearic acid. What is also described is a method for preparing said niacin tablet and a method for reducing hyperemia. n EFFECT: tablets under the present invention show favourable characteristics of release, reduction of severity, length and number of cases of skin hyperemia, generally caused by niacin therapy. n 24 cl, 27 dwg, 30 tbl, 8 ex
priorityDate 2006-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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