http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2464575-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95ebb25a382f5a19c09b922999193a76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4ad8a8f85d9d66def9a7d8e60dd958f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de5e29807f6308281f7d90d71ea0fbd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efba401a94fa8bc6b46af4f461da2439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82e9e0776f35b41ea54c36f28ec211f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5294ba8dde459e3ef54422cadb9b44bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08d7bce72badf5a4da47fa5b3b1ceb70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f57d1759b97e925d75573af3a7132a92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b9e1cf9ccec4a3a4f05de2d64c6d505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e346a3dca9cd9e25ef7b8432b523b769 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7216df67f2823083ed1d494e728de489 |
| publicationDate | 2012-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2464575-C1 |
| titleOfInvention | Method for determining functional state of blood plasma myeloperoxidase |
| abstract | FIELD: medicine. n SUBSTANCE: method involves introducing a substrate of o-dianisidine into blood plasma dissolved in a buffer solution, spectrophotometry of oxidation rate after adding hydrogen peroxide and determination of peroxidase activity of myeloperoxidase by a difference of o-dianisidine oxidation rates in the absence and in the presence of 4-aminobenzoic acid hydrazide. Additionally, the concentration of blood plasma myeloperoxidase is determined by introducing rat's affine myeloperoxidase antibodies into plate wells followed by adding plasma samples and myeloperoxidase standard. It is added with rabbit's myeloperoxidase antibodies and horseradish peroxide-conjugated rabbit's IgG antibodies. Then a myeloperoxidase specific activation coefficient C sa is calculated as a relation of enzyme activity to its concentration. If the values C sa is more than 1.65 optical density units/pg/min, the disturbed functional state of myeloperoxidase is stated. n EFFECT: invention provides fast and reliable determination of the functional state of blood plasma myeloperoxidase that enables predicting developing a number of diseases, improving diagnoses and taking well-timed actions aiming at enzyme strength control. n 2 ex, 3 dwg |
| priorityDate | 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.