Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_515093f38ac08a173af9353bcd2861d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d26b84b7c3216b92024914625f61525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18930545be38313c2d7c10140d8a2e8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bb3b54f834400ea2730674f17d3fd03 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate |
2011-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_149d87001bd8a82cf6f8515f645fd008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e89c61c10888abe3241497ac16bd4a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22460353da8110d3f5f198429e31f021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc87c8f0fa4191ddde6f24d016d1a909 |
publicationDate |
2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2460529-C1 |
titleOfInvention |
Drug possessing actoprotective, antihypoxic, neuroprotective, antiamnestic and thermoprotective activity |
abstract |
FIELD: medicine. n SUBSTANCE: what is offered is application of 2-ethyl-6-methyl-3-oxypiridinium L-asparaginate as a drug possessing actoprotective, antihypoxic, neuroprotectivem antiamnestic and thermoprotective activity. It is shown that actoprotective activity of this chemical compound 1 mg/kg exceeds that of the nearest analogue of the declared drug - Mexidol 5 and 10 mg/kg. Thermoprotective activity of this substance 5 mg/kg twice exceeds that of the nearest analogue of the declared drug - Mexidol 50 and 100 mg/kg. Antihypoxic, neuroprotective and antiamnestic activities of the declared drug in animals of various models exceed and/or are highly competitive with the nearest analogue Mexidol and the other reference preparations. n EFFECT: drug is used for the purpose of higher usual and extreme physical performance, as well as for treating acute and chronic disturbed cerebral circulation, including ischemic stroke and other conditions and diseases accompanied by depression of cognitive functions and neurodegeneration, including in ageing. n 10 tbl |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2584234-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2601622-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2662324-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2586301-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2743923-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2700419-C1 |
priorityDate |
2011-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |