Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db5e69e06b28f90dc831e39d907a7fc7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate |
2007-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1de38b8806144ed306db8f6f28b12da7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_170067cec3fba75da82ec8ff18416bd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7810a62de77016f00a004c6910edd38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd24b67a26e1f82e5cdf510b8ac02ea1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18fef8194b09ff8e4392e981024eb14d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd5f9f29709da35fd52784bed972cf92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f35a0f88bb491b55473dfdc25a0c82d2 |
publicationDate |
2012-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2456980-C2 |
titleOfInvention |
Granule and method for making thereof |
abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to pharmaceutics. A pharmaceutical granule is spherical or spheroidal and has volume density 0.6-1.3 g/ml and disintegration 0.5-5 minutes. Active pharmaceutical ingredients are preparations of Traditional Chinese Medicine, herbal preparations or their extracts with a nucleus made of an extract of Traditional Chinese Medicine or herbal preparations, and a pharmaceutically acceptable carrier. The content of the pharmaceutically acceptable carrier with respect to total granule weight makes 10-60 wt %. The granule diameter can be equal to 700-1500 mcm. The granule nucleus diameter can be equal to 200-750 mcm. The granule can be also coated with a layer of 2-5 wt % with respect of total granule weight. A method for making the granules consists in introducing initial granules into a layer of a fluidised material as an excipient; the active pharmaceutical ingredients are prepared in the form of a suspension or a solution of the viscosity controlled within 6.0-9.8 MPa·s with using a viscosity-control agent; then they are sprayed over a surface of the initial granule for making a finished granule. n EFFECT: granules possess fast disintegration, contain a small amount of the carrier and contain a low single dose. n 12 cl, 5 ex |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2712279-C2 |
priorityDate |
2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |