abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to compounds of formula (I) wherein R 4 represents a group of formula (II) and R 1 , R 2 , R 3 , R 5 and X are those as specified in the patent claim. n EFFECT: preparing the pharmaceutical composition applicable in treating chronic obstructive pulmonary disease and containing the compound of formula (I). n 8 cl, 3 tbl, 39 ex |