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filingDate 2010-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ea215b487a30e736840d0a95ebca196
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publicationDate 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2448701-C2
titleOfInvention Pharmaceutical composition for treating and/or preventing arterial hypertension
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: there is offered a pharmaceutical composition for treating and/or preventing arterial hypertension containing an angiotensin converting enzyme (ACE) inhibitor and N-acetyl-5-methoxytriptamine (melatonin) in the following proportions: ACE inhibitor - 2-4; N-acetyl-5-methoxytriptamine (melatonin) - 2-8; excipients - up to 100 mg with the ACE inhibitor being presented by the compounds specified in a group of enalapril, captopril, perindopril, lisinopril, fozinopril, quinapril, spirapril. The pharmaceutical composition may be presented by a solid dosage form - a tablet, a film-coated tablet, a softgel capsule, a solid gel capsule, by a soft dosage form - a rectal suppositorium. n EFFECT: providing a therapeutically significant effect (stable night-time blood pressure profile) and a lower risk of side effects due to using the doses low for the ACE inhibitors specified above have been shown. n 3 cl, 3 tbl
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