http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2448092-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fda45c540f11df3a7fe71d54a70562a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-88 |
| filingDate | 2007-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973b8b060d3d96413c1a6edf783e070c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11cf67abbc01df86f5ca4734ed0307a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b6055f73d8a02a9cb6d87413bffba8a |
| publicationDate | 2012-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2448092-C2 |
| titleOfInvention | Acetic acid (3-amino-1,2,3,4-tetrahydro-9-h-carbazol-9-yl) derivatives |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to a novel derivative of (3-amino-1,2,3,4-tetrahydro-9-H-carbazol-9-yl)acetic acid of formula where: R 1 , R 2 , R 3 and R 4 independently denote H, C 1-5 -alkyl, C 1-5 -alkoxy, C 2-7 -alkenyl, halogen, NO 2 , CN, halo-C 1-6 -alkoxy, halo-C 1-6 -alkyl, C 1-6 -alkylsulphonyl, formyl; R 5 denotes H, C 2-7 -alkenyl, C 1-6 -alkyl, C 3-10 -cycloalkyl-C 1-4 -alkyl, C 1-3 -alkoxy-C 1-4 -alkyl, aryl-C 1-4 -alkyl, aryloxy-C 1-4 -alkyl, where aryl denotes an unsubstituted mono- or disubstituted group, independently selected from C 1-2 -alkylenedioxy, C 1-4 -alkoxy, C 1-4 -alkyl, halogen, CF 3 , CF 3 O; R 6 denotes aryl-C 1-3 -alkoxy-C 1-3 -alkoxycarbonyl, aryl-C 1-3 -alkoxycarbonyl, aryl-C 1-3 -alkylaminocarbonyl, aryl-C 1-6 -alkylcarbonyl, aryl-C 1-3 -alkoxy-C 1-3 -alkylcarbonyl, arylcarbonyl-C 1-4 -alkylcarbonyl, aryloxy-C 1-3 -alkylcarbonyl, C 3-10 -cycloalkyl-C 1-3 -alkylcarbonyl, diaryl-C 1-3 -alkylcarbonyl, heteroaryl-C 1-3 -alkylcarbonyl, aryl-C 3-6 -cycloalkylcarbonyl, R 7 -C 1-4 -alkylcarbonyl, where the bridge C 1-4 -alkyl group can further be monosubstituted with aryl, and R 7 denotes arylaminocarbonyl, heteroarylaminocarbonyl, C 1-6 -alkylaminocarbonyl, aryl-C 1-3 -alkylaminocarbonyl, where aryl denotes phenyl, naphthyl, which are unsubstituted, mono- or disubstituted with a group independently selected from C 1-2 -alkylenedioxy group, C 1-6 -alkoxy group, C 1-6 -alkyl, C 1-6 -alkylsulphonyl, halogen, hydroxy group, halo-C 1-6 -alkyl, halo-C 1-6 -alkoxy group, C 1-6 -alkylthio group and C 1-4 -alkoxycarbonylamino group, and heteroaryl denotes a 5-10-member aromatic ring system, where 1-3 of said atoms are heteroatoms selected N, O, S, or pharmaceutically acceptable salts thereof. n EFFECT: compounds have hCRTH-2 antagonist activity, which allows for their use in a pharmaceutical composition. n 14 cl, 12 tbl, 251 ex |
| priorityDate | 2006-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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