| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to biochemistry and represents an isolated human or humanised antibody or its functional fragment which is specific to human GM-CSF. Also, there are presented variable heavy and light chains of the antibody, isolated nucleic acid sequences, an expression vector, a host cell, a pharmaceutical composition and a method of treating a GM-CSF-related condition. n EFFECT: invention may be used for treating the GM-CSF-related diseases for the diagnostic purposes, as well as for further studying of the GM-CSF role in progression of various diseases. n 102 cl, 21 dwg, 8 tbl, 7 ex |