http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2444378-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0be538603ccd261de5e6dd32bd4d4c51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad8d2e91732feb626589e8d0735b7496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24079e04a40633d1fe5c6bee0f2890ee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
| filingDate | 2010-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1bc41fe935418c1b336e329fcd88442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10ff52a750c6b0c18b9570cd16e945bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa9d498efbbdd72c00e2000693f1aa54 |
| publicationDate | 2012-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2444378-C1 |
| titleOfInvention | Method of treating coronary insufficiency in simulated myocardial ischemia |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to experimental medicine and can be used for developing molecular methods of treating coronary insufficiency. For this purpose, the simulated myocardial ischemia requires experimental myocardial injections of an endotheliocyte growth factor gene in the form of the phVEGF165 vector at 50-100 mcg/cm 2 of an ischemic region at an area pitch of 5 mm. 2-dimethylaminoethanol is added to the vector preparation to provide more effective myocardiocyte transfection. n EFFECT: unlike peptide growth factors requiring the regular administration, the use of a gene construct with the endotheliocyte growth factor gene introduced in a single dose according to the developed method provides the intensified myocardial construct delivery and the activation of a greater number of cells involved in angiogenesis that promotes repaired perfusion in the ischemic myocardium region. n 2 ex, 4 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2663643-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2572798-C1 |
| priorityDate | 2010-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.