| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to compounds of general formula n , n where R 1 represents CH 3 ; R 2 represents halogeno or CN; R 3 represents H or CH 3 ; R 4 represents H or CH 3 ; n represents 0, 1 or 2; and to their pharmaceutically acceptable salts. Also, the invention refers to a pharmaceutical composition and to application of the compounds of formula (I) in preparing a drug exhibiting antagonist activity in relation to CX 3 CR1 receptor. n EFFECT: provided the compounds of formula (I) as CX 3 CR1 receptor antagonists. n 20 cl, 1 tbl, 3 dwg, 10 ex |