| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: present invention refers to new 2-thyoxanthene derivatives, namely to a compound of formula or its pharmaceutically acceptable salt, representing: 3-(2-ethoxy-2-methylpropyl)-2-thyoxantene; 3 (2-propoxy-2-methylpropyl)-2-thyoxanteme; 3-(2-methoxy-2-methylpropyl)-2-thyoxantene; 3 (2-isopropoxyethyl)-2-thyoxantene; 3 (2-ethoxypropyl)-2-thyoxantene; 3 (2S-ethoxypropyl)-2-thyoxantene; 3-(2R-ethoxypropyl)-2-thyoxantene. Also, the invention refers to a pharmaceutical composition on the basis of the compound of formula I, to application of the compound of formula I in preparing a drug. n EFFECT: new 2-thyoxantene derivatives effective for MPO (myeloperoxidase) enzyme inhibition. n 9 cl, 1 tbl, 6 ex |