| abstract |
FIELD: medicine. n SUBSTANCE: invention relates to medicine, namely to treatment of infectious diseases and oncology and can be used in treatment of persisting infection, angioimmunoblastic lymphoma or nodular with lymphoid prevalence Hodgkin's lymphoma. Method includes introduction of compound, which reduces activity or expression of member of family CD28, where said member of CD28 family is selected from group, consisting of PD-1, CTLA-4, BTLA and their functional fragment and version. n EFFECT: application of invention makes it possible to increase efficiency of treatment of persisting infection, angioimmunoblastic lymphoma or nodular with lymphoid prevalence Hodgkin's lymphoma. n 36 cl, 8 dwg, 14 ex |