http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2433401-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f01f4524885ab6b6be7255d42b7c0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_009bcd298b2f9ea157869316cac2902a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2010-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad2a0388eb4c5ae245cef3a60c342545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc5567f2e39a6eccfc5ccdd657106c22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3a329bf0b151adaa06d3c40199afb3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6305970cb74f4c87affa46819df8192e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa266f31b87e60273e327c0a3a03c8dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90f582148cb44e9a3ad4063c6434c43 |
| publicationDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2433401-C1 |
| titleOfInvention | Method of predicting risk of development of therapeutic resistance in patients with bronchial asthma |
| abstract | FIELD: medicine. n SUBSTANCE: invention describes method of predicting risk of development of therapeutic resistance in patients with bronchial asthma, by analysis of patients blood 3 month after beginning of treatment, DNA, separated from lymphocytes of peripheral venous patients blood, is analysed, values of levels of genes INC2, INC3, GJA8, SV2 expression are determined by microchips Affymetrix and probability of relating individuum to group with high risk of developing therapeutic resistance and low risk of therapeutic resistance development, and, R1 for individuums with high risk of therapeutic resistance development is estimated by formula: R1=-351.966-, 274*INC2+46.608*INC3+129.530*GLA8+105.438*SV2A, where 274; 46.608; 129.530; 105.438 - numeric values are coefficients; (-351.966) is constant for individuums with high risk of BA development; INC2, INC3, GJA8, SV2 are genotytpes, and R2 for individuums with low risk of therapeutic resistance development is calculated by formula: R2=-403.217-64.874*INC2+55.603*INC3+141.648*GJA8+116.342*SV2A, where 64.874; 55.603; 141.648; 116.342 are numeric values which are coefficients; (-403.217) is constant for individuums with high risk of BA and at R1>R2 high risk is predicted , and at R1<R2 low risk of therapeutic resistance is predicted in patient with bronchial asthma. n EFFECT: increase of accuracy and self-descriptiveness. n 4 ex, 3 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2583948-C1 |
| priorityDate | 2010-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.