abstract |
FIELD: medicine. n SUBSTANCE: claimed is version of neutral metaloproteinase of wild type Bacillus, which has, at least, 80% identity with sequence, presented in description and having mutations in amino acid sequence in positions, also described in description. Described is method of ferment obtaining, which includes transformation of host-cell by vector, which contains polynucleotide, which codes one of metaloproteinase versions, and culturing of transformed cell in suitable conditions. Described are purifying composition, which contains claimed ferment, and method of fabric and textile purification, which includes stage of bringing surface and/or product from fabric or textile into contact with purifying composition. n EFFECT: claimed invention makes it possible to expand spectrum of means applied for surfaces purification, products of fabric or textile. n 28 cl, 12 tbl, 35 dwg, 29 ex |