abstract |
FIELD: medicine. n SUBSTANCE: what is described is an antibody molecule which selectively binds with a cellular surface ICAM-1 and if bound with ICAM-1, induces apoptosis in a target cell, and a nucleic acid molecule coding said antibody. Also, methods and pharmaceutical compositions for apoptosis induction and application thereof are presented. n EFFECT: invention allows producing molecules for cell apoptosis induction. n 33 cl, 11 dwg, 3 tbl, 6 ex |