Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2b0ede063942517e95f4fd0482963f1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-529 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 |
filingDate |
2006-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_832793adb8c280ff2aa9a789289c3967 |
publicationDate |
2011-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2429848-C2 |
titleOfInvention |
Compositions for treating systemic mastocytosis |
abstract |
FIELD: medicine. ^ SUBSTANCE: application involves a combination of AMN107 and PKC412 tyrosine kinase inhibitors for preparing a therapeutic agent for treating systemic mastocytosis (SM), including associated with oncogenic mutation KIT-D816V. The use of the invention enables higher clinical effectiveness of treating SM due to synergetic mast cell growth inhibition under action of the AMN107 and PKC412 combination. ^ EFFECT: higher efficacy of the composition. ^ 3 cl, 3 tbl, 17 dwg, 2 ex |
priorityDate |
2005-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |