abstract |
FIELD: medicine. n SUBSTANCE: there are offered methods for determining therapeutic efficacy of insulin-like growth factor-1 receptor (IGF-1R) antagonists. The methods are based on detecting and counting the IGF-1R expressing circulating tumour cells. n EFFECT: invention can be used for screening and definition of a stage of a cancer, developing therapeutic regimens, monitoring of response to treatment and recurrent cancer. n 12 cl, 4 ex, 6 dwg |