abstract |
FIELD: chemistry. ^ SUBSTANCE: disclosed are antibodies which specifically bind the human Oncostatin M (hOSM) site II and inhibit reaction between hOSM and gp130. The invention also discloses a polynucleotide, a host cell, a vector, treatment methods and other uses of antibodies. ^ EFFECT: invention can be effectively used to treat diseases mediated by the reaction between hOSM and gp130. ^ 31 cl, 52 dwg, 5 tbl, 16 ex |