abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to a method of producing N-methyl-4-benzylcarbamidopyridinium iodide (MBI), which is used as substance in medicinal agents, involving reaction of isonicotinic acid with benzylamine at temperature 160-185°C and molar ratio 1.0:1.2 and alkylation of the obtained benzylamide of isonicotinic acid with methyl iodide at 40-50°C and molar ratio 1.0:1.2. n EFFECT: high output of the end product and low solvent consumption. n 2 cl, 2 tbl, 10 ex |