http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2425049-C2

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3873
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-386
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38
filingDate 2007-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de606758c51b8e5928fbe51e41e91c36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6337a62070ffff9e28c5ce7139e4dbcb
publicationDate 2011-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2425049-C2
titleOfInvention Method of producing biphosphonic acids and their salts
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: present invention refers to a method of producing biphosphonic acids and their pharmaceutically acceptable salts applied in medicine. In the offered method, the compounds of general formula I or their pharmaceutically acceptable salts where R1 represents alkyl, arylalkyl, an aromatic or heteroaromatic group, are produced by a reaction of carboxylic acid of formula II or its salts, formula II in which R1 has said values, with phosphorous acid and phosphorous trichloride in an aprotonic polar solvent selected from N,N'-dimethylethylene urea (DMEU), N,N'-dimethylpropylene urea (DMPU), 1-methyl-2-pyrrolidone (NMP) or their mixtures. n EFFECT: new method of producing biologically active compounds is implemented. n 14 cl, 4 ex
priorityDate 2006-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 48.