http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2423980-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 |
filingDate | 2005-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eda9537a88d58a32d35c6e842ca4b76b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43773430a16814102310345553c51102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1895df86b5a55fee330bf241ca1f1dc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72160884f037aeb266d6efcace9ed993 |
publicationDate | 2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2423980-C2 |
titleOfInvention | Combinations containing epothilones and protein kinase inhibitors and pharmaceutical application thereof |
abstract | FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to drugs, and concerns a combination for treating glioma containing: (a) an epothilone derivative of formula (I') and (b) a protein kinase inhibitor {6-[4-(4-ethylpiperazine-1-ylmethyl)phenyl]-7N-pyrrolo[2,3-d]pyrimidine-4-yl}(1-phenylethyl)amine wherein the active ingredients (a) and (b) in each case are present in a free form or in the form of a pharmaceutically acceptable salt in an effective amount, and optionally at least one pharmaceutically acceptable carrier for concurrent, separate or consequent administration. What is disclosed is a pharmaceutical composition for treating glioma, application of the combination for preparing the drug and a market package. ^ EFFECT: combination under the invention shows a synergetic effect in treating glioma ^ where R, R' and Z have the values specified in formula. ^ 9 cl |
priorityDate | 2004-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.